Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199053 | 0.89 | TAAR1 (0.50) | CHRM2CHRM1CHRM3TAAR1MEN1 | |
| SCHEMBL8206393 | 0.89 | TAAR1 (0.43) | CHRM2CHRM1CHRM3TAAR1ROCK2 | |
| SCHEMBL8199243 | 0.83 | GRIN2B (0.46) | TAAR1SIGMAR1 | |
| SCHEMBL8206923 | 0.83 | TAAR1 (0.54) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8206646 | 0.82 | TACR1 (0.42) | CHRM2CHRM1CHRM3TAAR1MEN1 | |
| SCHEMBL8206100 | 0.81 | HSD11B1 (0.42) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8209834 | 0.81 | GRIN2B (0.46) | TAAR1SIGMAR1 | |
| SCHEMBL8207099 | 0.79 | KDM4E (0.46) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL8207012 | 0.78 | KDM4E (0.47) | CHRM2CHRM1CHRM3CYP1A2CYP3A4 | |
| SCHEMBL8208907 | 0.78 | CHRM2 (0.40) | CHRM2CHRM1CHRM3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |