Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206100 | 0.94 | HSD11B1 (0.42) | CHRM2CHRM3CHRM1SMN1; SMN2HSD11B1 | |
| SCHEMBL8206448 | 0.85 | CHRM2 (0.41) | CHRM2CHRM3CHRM1SMN1; SMN2CYP2C19 | |
| SCHEMBL8199243 | 0.85 | GRIN2B (0.46) | GRIN1GRIN2B | |
| SCHEMBL8197966 | 0.82 | CHRM3 (0.40) | CHRM2CHRM3CHRM1SMN1; SMN2CYP2C19 | |
| SCHEMBL8199188 | 0.81 | GRIN2B (0.40) | CHRM2CHRM3CHRM1GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL8209834 | 0.81 | GRIN2B (0.46) | GRIN1GRIN2B | |
| SCHEMBL8209728 | 0.80 | HRH1 (0.42) | CHRM2CHRM3CYP1A2CYP2C19GRIN1 | |
| SCHEMBL8199090 | 0.80 | GRIN2B (0.43) | CHRM2CHRM3GRIN1GRIN2BALDH1A1 | |
| SCHEMBL8207085 | 0.80 | POLB (0.36) | CHRM2CHRM3CHRM1CYP2C19HSD11B1 | |
| SCHEMBL8199053 | 0.80 | TAAR1 (0.50) | CHRM2CHRM3CHRM1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | claimed |
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |