Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207262 | 1.00 | ACHE (0.55) | ACHEMEN1KMT2AGAAGPR55 | |
| SCHEMBL8183861 | 0.78 | SIRT1 (0.64) | MAOAMAOBADAMTS5MMP13MMP3 | |
| SCHEMBL8183862 | 0.78 | SIRT1 (0.64) | MAOAMAOBADAMTS5MMP13MMP3 | |
| SCHEMBL5576896 | 0.78 | NTRK1 (0.51) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL1249365 | 0.78 | PTPN1 (0.69) | ACHEMEN1KMT2AKDM4EMAOA | |
| SCHEMBL5475436 | 0.78 | NTRK1 (0.74) | ACHEMEN1KMT2AGAAGPR55 | |
| SCHEMBL14448938 | 0.78 | NTRK1 (0.74) | ACHEMEN1KMT2AGAAGPR55 | |
| SCHEMBL12891965 | 0.78 | PTPN1 (0.69) | ACHEMEN1KMT2AKDM4EMAOA | |
| SCHEMBL5475438 | 0.78 | NTRK1 (0.74) | ACHEMEN1KMT2AGAAGPR55 | |
| SCHEMBL1249362 | 0.78 | PTPN1 (0.69) | ACHEMEN1KMT2AKDM4EMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018745-A1 | OXAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |