Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 4/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25782046 | 0.81 | FAAH (0.37) | — | |
| SCHEMBL6500352 | 0.80 | DPP7 (0.43) | — | |
| SCHEMBL9045357 | 0.80 | DPP7 (0.43) | — | |
| SCHEMBL1065941 | 0.76 | MAPT (0.44) | CYP1A2CYP3A4CYP2C19HTTTLR2 | |
| SCHEMBL25055940 | 0.76 | MAPT (0.44) | CYP1A2CYP3A4CYP2C19HTTTLR2 | |
| SCHEMBL753367 | 0.75 | SLC1A2 (0.37) | CYP3A4TSHRALDH1A1 | |
| SCHEMBL5607813 | 0.75 | NOS3 (0.54) | CYP1A2CYP3A4CYP2C19HTTNOS3 | |
| SCHEMBL2757451 | 0.75 | NOS3 (0.54) | CYP1A2CYP3A4CYP2C19HTTNOS3 | |
| SCHEMBL6629003 | 0.75 | FAAH (0.38) | — | |
| SCHEMBL6628997 | 0.75 | FAAH (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021235-A2 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 2-(QUINOLIN-5-YL)-4,5 DISUBSTITUTED-AZOLE DERIVATIVES | SCHERING CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |