Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206225 | 0.93 | TDP1 (0.54) | TDP1HSP90AA1MEN1KMT2AALDH1A1 | |
| SCHEMBL8206042 | 0.91 | TDP1 (0.53) | TDP1HSP90AA1MEN1KMT2AALDH1A1 | |
| SCHEMBL8200394 | 0.91 | HPGD (0.55) | TDP1HSP90AA1MEN1KMT2AALDH1A1 | |
| SCHEMBL7881130 | 0.89 | TDP1 (0.60) | TDP1HSP90AA1MEN1KMT2AALDH1A1 | |
| SCHEMBL8200033 | 0.88 | TDP1 (0.55) | TDP1HSP90AA1MEN1KMT2AALDH1A1 | |
| SCHEMBL8199987 | 0.87 | LMNA (0.57) | TDP1HSP90AA1MEN1KMT2AALDH1A1 | |
| SCHEMBL7889265 | 0.84 | GRIN2C (0.60) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL8200373 | 0.83 | TDP1 (0.53) | TDP1HSP90AA1MEN1KMT2AALDH1A1 | |
| SCHEMBL7890829 | 0.83 | GRIN2C (0.56) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL8200327 | 0.82 | KMT2A (0.52) | TDP1MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |