Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 6/20 | 0.53 |
| ▸ | CA1 | P00915 | 6/20 | 0.53 |
| ▸ | CA2 | P00918 | 6/20 | 0.53 |
| ▸ | CA7 | P43166 | 6/20 | 0.53 |
| ▸ | CA9 | Q16790 | 6/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43683 | 0.89 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL27683331 | 0.82 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL6233392 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL30678268 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL5986749 | 0.82 | LMNA (0.50) | HTTMAPTALDH1A1LMNACYP4F2 | |
| SCHEMBL30242194 | 0.82 | LMNA (0.50) | HTTMAPTALDH1A1LMNACYP4F2 | |
| SCHEMBL27910803 | 0.82 | MAPT (0.39) | NPC1RAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL23471093 | 0.81 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HTTMAPT | |
| SCHEMBL4186126 | 0.80 | TSHR (0.55) | NPC1RAB9ASMN1; SMN2MAPTCA12 | |
| SCHEMBL6252421 | 0.79 | FURIN (0.41) | HTTMAPTALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110282009-A1 | Free-radical Curable Isobutylene-rich Polymers | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-11-17 | — | — | US | disclosed |