Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650722 | 0.80 | CTNNB1 (0.41) | KDM4EALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL28156609 | 0.74 | ALDH1A1 (0.52) | KDM4EKLK7ALDH1A1HSD17B10GAA | |
| SCHEMBL29660570 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10RAB9AL3MBTL1 | |
| SCHEMBL4596211 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10RAB9AL3MBTL1 | |
| SCHEMBL14917040 | 0.70 | FABP4 (0.67) | KDM4EALDH1A1GAAL3MBTL1DHODH | |
| SCHEMBL5177389 | 0.69 | KDM4E (0.52) | KDM4EKLK7ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL2825174 | 0.68 | ALDH1A1 (0.76) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL27971255 | 0.68 | KDM4E (0.48) | KDM4EKLK7ALDH1A1HSD17B10GAA | |
| SCHEMBL7655588 | 0.68 | PLA2G2A (0.45) | KDM4EALDH1A1HSD17B10HPGDDHODH | |
| SCHEMBL18222218 | 0.68 | FABP4 (0.51) | KDM4EALDH1A1GAAL3MBTL1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |