SCHEMBL8208058

SCHEMBL8208058

CCOC(CO)C(CO)OCCO

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.35
MGAM O43451 1/20 0.33
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16008963 0.89 ALDH1A1 (0.37) ALDH1A1LMNATHRBMGAM
SCHEMBL6036788 0.81 TSHR (0.50) ALDH1A1LMNATHRBMGAMTSHR
SCHEMBL10383982 0.81 TSHR (0.34) ALDH1A1THRBTSHR
SCHEMBL6245770 0.81 LMNA (0.37) ALDH1A1LMNA
SCHEMBL1482928 0.77
SCHEMBL9019108 0.75 ALDH1A1 (0.42) ALDH1A1LMNATHRBTSHRMAPK1
SCHEMBL2499893 0.75 ALDH1A1 (0.42) ALDH1A1LMNATHRBTSHRMAPK1
SCHEMBL11208111 0.75 TDP1 (0.36) ALDH1A1TSHRMAPK1
SCHEMBL13497198 0.75 TDP1 (0.36) ALDH1A1TSHRMAPK1
SCHEMBL3856267 0.74 THRB (0.61) ALDH1A1LMNATHRBTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6034281-A Purification of diethylene glycol monoethyl ether FERRO CORPORATION (US) 2000-03-07 US disclosed