Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27910796 | 0.86 | PTGS2 (0.42) | SMN1; SMN2NPC1RAB9AHTTMAPT | |
| SCHEMBL2223288 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AHTTMAPT | |
| SCHEMBL21112030 | 0.83 | PTGS2 (0.39) | SMN1; SMN2NPC1RAB9AHTTMAPT | |
| SCHEMBL43683 | 0.82 | NPC1 (0.65) | SMN1; SMN2NPC1RAB9AHTTMAPT | |
| SCHEMBL27910782 | 0.82 | MAPT (0.42) | SMN1; SMN2NPC1RAB9AHTTMAPT | |
| SCHEMBL498199 | 0.81 | P4HB (0.56) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL2904118 | 0.81 | UNG (0.44) | ALDH1A1MEN1KMT2APTGS2TP53 | |
| SCHEMBL821210 | 0.80 | CA12 (0.61) | SMN1; SMN2NPC1RAB9AHTTMAPT | |
| SCHEMBL27910783 | 0.79 | TSHR (0.39) | SMN1; SMN2NPC1RAB9APTGS2LMNA | |
| SCHEMBL28770770 | 0.78 | UNG (0.42) | ALDH1A1MEN1KMT2APTGS2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110282009-A1 | Free-radical Curable Isobutylene-rich Polymers | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-11-17 | — | — | US | disclosed |