Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CFTR | P13569 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208103 | 1.00 | MITF (0.69) | MITFKMT2AAKR1B1CA9MAPK1 | |
| SCHEMBL1904245 | 0.89 | MAPK1 (0.71) | KMT2AAKR1B1MAPK1 | |
| SCHEMBL1904243 | 0.89 | MAPK1 (0.71) | KMT2AAKR1B1MAPK1 | |
| SCHEMBL1904246 | 0.89 | MAPK1 (0.71) | KMT2AAKR1B1MAPK1 | |
| SCHEMBL15828869 | 0.83 | KMT2A (0.79) | MITFKMT2AMAPK1CFTR | |
| SCHEMBL15831457 | 0.82 | KMT2A (0.98) | MITFKMT2ACA9MAPK1CFTR | |
| SCHEMBL15702367 | 0.82 | KMT2A (0.67) | MITFKMT2A | |
| SCHEMBL6886476 | 0.80 | MAPK1 (0.75) | MITFKMT2AMAPK1 | |
| SCHEMBL6886480 | 0.80 | MAPK1 (0.75) | MITFKMT2AMAPK1 | |
| SCHEMBL8172926 | 0.79 | AKR1B1 (0.69) | AKR1B1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018746-A1 | THIAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |