Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL11801759 | 0.83 | — | — | |
| Thiourea SCHEMBL22836739 | 0.79 | TSHR (0.50) | TSHRATMATRCA1CA2 | |
| Thiourea SCHEMBL22836742 | 0.79 | — | — | |
| Thiourea SCHEMBL11227959 | 0.79 | — | — | |
| Thiourea SCHEMBL4869268 | 0.73 | — | — | |
| Thiosulfuric Acid SCHEMBL8197744 | 0.73 | CA1 (0.35) | TSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL8907828 | 0.71 | CA5A (0.40) | TSHRCA1CA2 | |
| Thiourea SCHEMBL11881123 | 0.69 | TSHR (0.46) | TSHRATMATR | |
| Thiourea SCHEMBL11881110 | 0.69 | TSHR (0.46) | TSHRATMATR | |
| Urea SCHEMBL8087814 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6068853-A | CHRONOBIOLOGY IN THAT THE DRUG DELIVERY SYSTEM CAN BE DESIGNED TO MODULATE ACTIVE AGENT DELIVERY IN ACCORDANCE WITH BIOLOGICAL RHYTHMS; OSCILLATION CHEMICAL SYSTEM | NOVARTIS CORPORATION (US) | 2000-05-30 | — | — | US | claimed |
| EP-0755244-A1 | TEMPORALLY CONTROLLED DRUG DELIVERY SYSTEMS | Novartis AG (CH) | 1997-01-29 | — | — | EP | claimed |
| WO-1995028144-A1 | TEMPORALLY CONTROLLED DRUG DELIVERY SYSTEMS | CIBA-GEIGY AG (CH) | 1995-10-26 | — | — | WO | claimed |
| US-6068853-A | CHRONOBIOLOGY IN THAT THE DRUG DELIVERY SYSTEM CAN BE DESIGNED TO MODULATE ACTIVE AGENT DELIVERY IN ACCORDANCE WITH BIOLOGICAL RHYTHMS; OSCILLATION CHEMICAL SYSTEM | NOVARTIS CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0755244-A1 | TEMPORALLY CONTROLLED DRUG DELIVERY SYSTEMS | Novartis AG (CH) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028144-A1 | TEMPORALLY CONTROLLED DRUG DELIVERY SYSTEMS | CIBA-GEIGY AG (CH) | 1995-10-26 | — | — | WO | disclosed |