Thiourea

Thiourea

SCHEMBL22836739

N.N.NC(N)=S.O=S(O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ATM Q13315 1/20 0.50
ATR Q13535 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiourea SCHEMBL22836742 1.00
Thiourea SCHEMBL11801759 0.96
Thiourea SCHEMBL11227959 0.92
Thiourea SCHEMBL8208148 0.79 TSHR (0.38) TSHRATMATRCA1CA2
Urea SCHEMBL9650691 0.78
Urea SCHEMBL27522187 0.78 LMNA (0.55) TSHRCA1CA2MEN1LMNA
Thiourea SCHEMBL4869268 0.77
Sulfurous Acid SCHEMBL11852356 0.77
Thiourea SCHEMBL6900327 0.76
Sulfurous Acid SCHEMBL3388945 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024178529-A1 COLORANT COMPOSITION FOR DYEING KERATIN FIBERS AND KIT COMPRISING THE SAME L'OREAL (FR) 2024-09-06 WO claimed
CN-114269320-B Composition for dyeing keratin fibres and use thereof 莱雅公司 2025-04-08 CN disclosed
US-12144880-B2 Cosmetic composition for the oxidative dyeing of keratin fibres L'OREAL (FR) 2024-11-19 US disclosed
WO-2024178529-A1 COLORANT COMPOSITION FOR DYEING KERATIN FIBERS AND KIT COMPRISING THE SAME L'OREAL (FR) 2024-09-06 WO disclosed
US-20230414471-A1 COSMETIC COMPOSITION FOR THE OXIDATIVE DYEING OF KERATIN FIBRES L'OREAL (FR) 2023-12-28 US disclosed
US-11819562-B2 Composition for dyeing keratin fibres and use thereof L'OREAL (FR) 2023-11-21 US disclosed
US-11752082-B2 Cosmetic composition for the oxidative dyeing of keratin fibres L'OREAL (FR) 2023-09-12 US disclosed
WO-2023050168-A1 RETARDANT COMPOSITION AND DYE KIT COMPRISING THEREOF L'OREAL (FR) 2023-04-06 WO disclosed
WO-2023272863-A1 COMBINATION FOR DYEING KERATIN FIBERS AND USE THEREOF L'OREAL (FR) 2023-01-05 WO disclosed
WO-2023272610-A1 DYE KIT L'OREAL (FR) 2023-01-05 WO disclosed
CN-114423500-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-04-29 CN disclosed
CN-114364367-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-04-15 CN disclosed
WO-2020259218-A1 COMPOSITION FOR DYEING KERATIN FIBRES AND USE THEREOF L'OREAL (FR) 2020-12-30 WO disclosed
WO-2020258731-A1 COMPOSITION FOR DYEING KERATIN FIBERS L'OREAL (FR) 2020-12-30 WO disclosed
WO-2020259214-A1 COMPOSITION FOR DYEING KERATIN FIBRES AND USE THEREOF L'OREAL (FR) 2020-12-30 WO disclosed
WO-2020258220-A1 COSMETIC COMPOSITION FOR THE OXIDATIVE DYEING OF KERATIN FIBRES L'OREAL (FR) 2020-12-30 WO disclosed
WO-2020259217-A1 COMPOSITION FOR DYEING KERATIN FIBRES AND USE THEREOF L'OREAL (FR) 2020-12-30 WO disclosed
WO-2020259215-A1 COMPOSITION FOR DYEING KERATIN FIBRES AND USE THEREOF L'OREAL (FR) 2020-12-30 WO disclosed
WO-2020258732-A1 COMPOSITION FOR DYEING KERATIN FIBERS L'OREAL (FR) 2020-12-30 WO disclosed
WO-2020258730-A1 COMPOSITION FOR DYEING KERATIN FIBERS AND USE THEREOF L'OREAL (FR) 2020-12-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230414471-A1 COSMETIC COMPOSITION FOR THE OXIDATIVE DYEING OF KERATIN FIBRES KRT18, TYR, AKR1A1 TSHR 1826/4885ATM 355/4885ATR 915/4885
US-11752082-B2 Cosmetic composition for the oxidative dyeing of keratin fibres KRT18, AKR1C1, CUTA TSHR 3601/4885ATM 1316/4885ATR 3645/4885
US-12144880-B2 Cosmetic composition for the oxidative dyeing of keratin fibres KRT18, TYR, AKR1A1 TSHR 1826/4885ATM 355/4885ATR 915/4885
US-11819562-B2 Composition for dyeing keratin fibres and use thereof KRT18, KLK5, JUP TSHR 3647/4885ATM 2572/4885ATR 2709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.