Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Thiourea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL11881110 | 0.89 | TSHR (0.46) | — | |
| Thiourea SCHEMBL11881123 | 0.89 | TSHR (0.46) | — | |
| Urea SCHEMBL4966000 | 0.81 | — | — | |
| Thiourea SCHEMBL11801759 | 0.81 | — | — | |
| Sulfurous Acid SCHEMBL8055702 | 0.81 | — | — | |
| Sulfurous Acid SCHEMBL10590522 | 0.81 | — | — | |
| Sulfurous Acid SCHEMBL1533868 | 0.80 | CA1 (0.50) | — | |
| Sulfurous Acid SCHEMBL29410199 | 0.80 | CA1 (0.50) | — | |
| Sulfurous Acid SCHEMBL889 | 0.80 | — | — | |
| Sulfurous Acid SCHEMBL8846189 | 0.80 | CA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371356-B2 | Method for the production of precipitated calcium carbonate with a high degree of brightness | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-13 | — | — | US | disclosed |
| US-20050158226-A1 | Method for the production of precipitated calcium carbonate with a high degree of brightness | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | disclosed |
| US-3976812-A | Photoconductive cells | EASTMAN KODAK COMPANY (US) | 1976-08-24 | — | — | US | disclosed |