SCHEMBL8208355

SCHEMBL8208355

Cc1ccc(C=O)c(I)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 1/20 0.43
SRC P12931 1/20 0.43
ERN1 O75460 3/20 0.41
CYP2A6 P11509 2/20 0.41
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
MCL1 Q07820 1/20 0.38
PIM3 Q86V86 1/20 0.37
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NQO2 P16083 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13106397 0.82 SRC (0.47) ALDH1A1KDM4EGAATSHRSRC
SCHEMBL2888296 0.78 ERN1 (0.52) ALDH1A1KDM4EGAATSHRSRC
SCHEMBL15982250 0.77 CYP2A6 (0.47) ALDH1A1KDM4EGAATSHRCYP2A6
SCHEMBL29437223 0.76 ALDH1A1 (0.52) ALDH1A1KDM4EGAATSHRSRC
SCHEMBL95501 0.76 ALDH1A1 (0.52) ALDH1A1KDM4EGAATSHRSRC
SCHEMBL95555 0.76 ERN1 (0.56) ALDH1A1TSHRERN1TDP1MEN1
SCHEMBL28468611 0.75 C1R (0.47) ALDH1A1KDM4EGAATSHRSRC
SCHEMBL5427296 0.74 TDP1 (0.64) ALDH1A1ERN1TDP1MEN1LMNA
SCHEMBL24014740 0.73 ERN1 (0.42) ALDH1A1KDM4ETSHRERN1TDP1
SCHEMBL2549468 0.73 ERN1 (0.52) ALDH1A1ERN1CYP2A6TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120117974-A Synthetic method for preparing di-deuterated primary alcohol by catalytic aldehyde hydrogenation and hydrogen-deuterium exchange reaction 中国科学院大连化学物理研究所 2025-06-10 CN claimed
CN-118026796-A Synthetic method for decarbonylation deuteration reaction of rhodium-catalyzed aldehyde compound 中国科学院大连化学物理研究所 2024-05-14 CN claimed
US-20180134674-A1 MAGL INHIBITORS H. LUNDBECK A/S (DK) 2018-05-17 US disclosed
US-6020332-A Fluorine-containing diphenyl acrylamide antimicrobial agents SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) 2000-02-01 US disclosed
EP-0860438-A1 Fluorine-containing diphenyl acrylamide antimicrobial agents Shenyang Research Institute of Chemical Industry (CN) 1998-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180134674-A1 MAGL INHIBITORS MAG, MAGI3, MGLL ALDH1A1 4349/4885KDM4E 984/4885GAA 1527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.