Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625680 | 0.79 | TSHR (0.38) | TSHRTHRBOPRM1DNM1MEN1 | |
| SCHEMBL29401979 | 0.73 | TSHR (0.42) | TSHRTHRBOPRM1DNM1MEN1 | |
| SCHEMBL11359903 | 0.73 | TSHR (0.36) | TSHRTHRBDNM1 | |
| SCHEMBL11368821 | 0.70 | TSHR (0.38) | TSHRTHRBOPRM1DNM1MEN1 | |
| SCHEMBL16740683 | 0.70 | TSHR (0.38) | TSHRTHRBOPRM1DNM1MEN1 | |
| SCHEMBL20582505 | 0.69 | OPRM1 (0.35) | TSHROPRM1ALDH1A1LMNA | |
| SCHEMBL1494464 | 0.67 | TSHR (0.47) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL3986839 | 0.67 | TSHR (0.47) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL1494509 | 0.67 | TSHR (0.47) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL1494519 | 0.67 | TSHR (0.47) | TSHRTHRBDNM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902106-A | Bistable ferroelectric smectic liquid crystal display device having particular orientation film | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1990-02-20 | — | — | US | claimed |
| EP-0286539-A1 | Bistable smectic ferroelectric liquid-crystal display | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1988-10-12 | — | — | EP | claimed |
| EP-0635747-B1 | Alignment film for liquid crystal and method for production thereof | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2000-06-28 | — | — | EP | disclosed |
| US-4902106-A | Bistable ferroelectric smectic liquid crystal display device having particular orientation film | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1990-02-20 | — | — | US | disclosed |
| EP-0286539-A1 | Bistable smectic ferroelectric liquid-crystal display | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1988-10-12 | — | — | EP | disclosed |