Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20582505 | 0.90 | OPRM1 (0.35) | TSHROPRM1ALDH1A1 | |
| SCHEMBL4816400 | 0.79 | — | — | |
| SCHEMBL8208358 | 0.79 | TSHR (0.36) | TSHRTHRBOPRM1DNM1MEN1 | |
| SCHEMBL10394448 | 0.68 | TRPM8 (0.43) | TSHRTHRBDNM1EPHX1 | |
| Decane SCHEMBL4607742 | 0.67 | TSHR (0.61) | TSHRTHRBOPRM1DNM1MEN1 | |
| Hexane SCHEMBL28833057 | 0.67 | OPRM1 (0.53) | TSHRTHRBOPRM1DNM1MEN1 | |
| Dodecane SCHEMBL28202232 | 0.67 | TSHR (0.61) | TSHRTHRBOPRM1DNM1MEN1 | |
| Heptane SCHEMBL17633521 | 0.67 | TSHR (0.61) | TSHRTHRBOPRM1DNM1MEN1 | |
| SCHEMBL30972164 | 0.66 | TSHR (0.89) | TSHRTHRBDNM1MEN1KMT2A | |
| SCHEMBL4621265 | 0.66 | TSHR (0.50) | TSHRTHRBDNM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019256-A1 | SILICONE ELASTOMER-BASED COMPOSITIONS, ARTICLES AND METHOD FOR PROTECTION AGAINST CORROSION | PETROENGE PETRÓLEO ENGENHARIA LTDA (BR) | 2012-02-16 | — | — | WO | disclosed |