Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 11/20 | 0.56 |
| ▸ | MTTP | P55157 | 11/20 | 0.56 |
| ▸ | SMO | Q99835 | 3/20 | 0.47 |
| ▸ | KLRK1 | P26718 | 3/20 | 0.44 |
| ▸ | MICA | Q29983 | 3/20 | 0.44 |
| ▸ | RAET1L | Q5VY80 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210367 | 0.93 | MTTP (0.52) | APOBMTTPSMOKDM4E | |
| SCHEMBL8211362 | 0.87 | MTTP (0.54) | APOBMTTPSMOKDM4E | |
| SCHEMBL8206850 | 0.86 | MTTP (0.58) | APOBMTTPSMOKDM4E | |
| SCHEMBL8200954 | 0.77 | MTTP (0.57) | APOBMTTPSMOKDM4E | |
| SCHEMBL8472708 | 0.76 | APOB (0.52) | APOBMTTPSMOKDM4E | |
| SCHEMBL8208154 | 0.76 | APOB (0.59) | APOBMTTPSMOKDM4E | |
| SCHEMBL6645543 | 0.75 | MTTP (0.61) | APOBMTTPSMOKDM4E | |
| SCHEMBL8208303 | 0.74 | APOB (0.62) | APOBMTTPSMOKDM4E | |
| Hydrochloric Acid SCHEMBL6803931 | 0.74 | MTTP (0.60) | APOBMTTPSMOKDM4E | |
| SCHEMBL8208669 | 0.72 | MTTP (0.57) | APOBMTTPSMOKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121283-A | Apo B-secretion/MTP inhibitory amides | PFIZER INC (US) | 2000-09-19 | — | — | US | disclosed |