Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 10/20 | 0.52 |
| ▸ | MTTP | P55157 | 9/20 | 0.52 |
| ▸ | SMO | Q99835 | 4/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975613 | 0.83 | APOB (0.43) | APOBMTTPSMOGAAMAPT | |
| SCHEMBL8206850 | 0.80 | MTTP (0.58) | APOBMTTPSMOKDM4EALDH1A1 | |
| Xenalipin SCHEMBL9094220 | 0.79 | MTTP (0.40) | APOBMTTP | |
| SCHEMBL8211362 | 0.77 | MTTP (0.54) | APOBMTTPSMOKDM4E | |
| SCHEMBL6645543 | 0.76 | MTTP (0.61) | APOBMTTPSMOKDM4EALDH1A1 | |
| SCHEMBL8208396 | 0.76 | APOB (0.56) | APOBMTTPSMOKDM4E | |
| SCHEMBL6974436 | 0.76 | MTTP (0.53) | APOBMTTPSMOCYP1A2CYP2C9 | |
| SCHEMBL8210367 | 0.76 | MTTP (0.52) | APOBMTTPSMOKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6803931 | 0.76 | MTTP (0.60) | APOBMTTPSMOKDM4EALDH1A1 | |
| SCHEMBL6964506 | 0.75 | APOB (0.44) | APOBMTTPSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | claimed |