Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205282 | 0.95 | CHRM3 (0.45) | CHRM3CACNA1CCHRM1CHRM5ALOX5 | |
| SCHEMBL8206274 | 0.92 | SLC18A3 (0.43) | CACNA1CL3MBTL1POLB | |
| SCHEMBL8209743 | 0.92 | SLC18A3 (0.43) | CACNA1CL3MBTL1POLB | |
| SCHEMBL8205248 | 0.91 | SLC18A3 (0.45) | CACNA1CL3MBTL1POLBOPRM1 | |
| SCHEMBL8206587 | 0.86 | SLC18A3 (0.47) | CHRM3ALOX5OPRM1 | |
| SCHEMBL8199247 | 0.86 | AGTR2 (0.42) | CHRM3CHRM1CHRM5CHRM2CHRM4 | |
| SCHEMBL8199191 | 0.85 | CHRM2 (0.38) | CHRM3CACNA1CCHRM1CHRM5CHRM2 | |
| SCHEMBL8209731 | 0.85 | HRH1 (0.39) | CHRM3CHRM1CHRM5CHRM2CHRM4 | |
| SCHEMBL8205356 | 0.84 | CHIT1 (0.41) | CHRM3CACNA1CCHRM1CHRM5CHRM2 | |
| SCHEMBL8199092 | 0.84 | KMT2A (0.40) | CHRM3CHRM1CHRM5CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |