SCHEMBL820880

SCHEMBL820880

ClOCc1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31655454 0.97 TSHR (0.57)
Formic Acid SCHEMBL3418146 0.86 ALDH1A1 (0.50)
Pyridine SCHEMBL9740364 0.86 TSHR (0.46)
Acetic Acid SCHEMBL7053200 0.86 ALDH1A1 (0.61)
SCHEMBL11798517 0.82 TSHR (0.43)
SCHEMBL27465014 0.79
SCHEMBL7915801 0.78 TSHR (0.55)
SCHEMBL177923 0.75 TSHR (0.67)
SCHEMBL27380 0.75 TSHR (1.00)
SCHEMBL5311581 0.75 TSHR (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 718 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115106085-B Application of composite photocatalyst in photocatalytic oxidation of aromatic alcohol coupling hydrogen 中国科学院理化技术研究所 2023-09-15 CN claimed
CN-116496148-A Process for removing o (p) chlorobenzyl alcohol impurity in o (p) chlorobenzaldehyde product 湖北源洹实业投资有限公司 2023-07-28 CN claimed
CN-116106344-A Method for monitoring polluted soil restoration process 中国科学院生态环境研究中心 2023-05-12 CN claimed
CN-115106085-A Application of composite photocatalyst in photocatalytic oxidation aromatic alcohol coupling hydrogen production 中国科学院理化技术研究所 2022-09-27 CN claimed
EP-3246328-B1 QUINAZOLINE HETEROCYCLIC COMPOUND AS EGFR KINASE INHIBITOR, AND PREPARATION AND APPLICATION THEREOF BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) 2020-07-22 EP claimed
CN-109106670-A A kind of novel desquamation compositions and preparation method 长沙小如信息科技有限公司 2019-01-01 CN claimed
US-10106508-B2 Quinazoline heterocyclic compound as EGFR kinase inhibitor and preparation and application thereof BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) 2018-10-23 US claimed
CN-107759763-A One kind is used for textile wash resistant retardant synergist and preparation method and application 北京中纺化工股份有限公司 2018-03-06 CN claimed
CN-107740278-A A kind of comb polyurethane flame-retardant water-repellent finishing agent and preparation method and application 北京中纺化工股份有限公司 2018-02-27 CN claimed
US-20170355683-A1 QUINAZOLINE HETEROCYCLIC COMPOUND AS EGFR KINASE INHIBITOR AND PREPARATION AND APPLICATION THEREOF BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) 2017-12-14 US claimed
US-20030099694-A1 Method for the improvement of transport across adaptable semi-permeable barriers IDEA AG (DE) 2003-05-29 US claimed
JP-2002533379-A 2002-10-08 JP claimed
US-20020064524-A1 Formulation for topical non-invasive application in vivo IDEA AG (DE) 2002-05-30 US claimed
EP-1189598-A1 A METHOD FOR THE IMPROVEMENT OF TRANSPORT ACROSS ADAPTABLE SEMI-PERMEABLE BARRIERS IDEA AG (DE) 2002-03-27 EP claimed
CN-1327382-A Improved formulation for topical non-invasive application in vivo IDEA INNOVAT DERMALE APPL GMBH (DE) 2001-12-19 CN claimed
EP-1140021-A1 IMPROVED FORMULATION FOR TOPICAL NON-INVASIVE APPLICATION IN VIVO IDEA AG (DE) 2001-10-10 EP claimed
WO-2001001963-A1 A METHOD FOR THE IMPROVEMENT OF TRANSPORT ACROSS ADAPTABLE SEMI-PERMEABLE BARRIERS IDEA AG (DE) 2001-01-11 WO claimed
WO-2001001962-A1 A METHOD FOR THE IMPROVEMENT OF TRANSPORT ACROSS ADAPTABLE SEMI-PERMEABLE BARRIERS IDEA AG. (DE) 2001-01-11 WO claimed
WO-2000038653-A1 IMPROVED FORMULATION FOR TOPICAL NON-INVASIVE APPLICATION IN VIVO IDEA AG. (DE) 2000-07-06 WO claimed
US-4297270-A ETH- OR PROPOXYLATED ESTER DERIVATIVES; DISPERSANTS; EMULSIFIERS; WETTING AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1981-10-27 US claimed