Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208906 | 1.00 | ERCC5 (0.45) | ERCC5FEN1HPGDGPR52MYC | |
| SCHEMBL9464464 | 0.80 | ERCC5 (0.52) | ERCC5FEN1HPGDGPR52MYC | |
| SCHEMBL9333335 | 0.78 | ERCC5 (0.50) | ERCC5FEN1HPGDGPR52MYC | |
| SCHEMBL9333326 | 0.78 | ERCC5 (0.50) | ERCC5FEN1HPGDGPR52MYC | |
| SCHEMBL9563141 | 0.77 | ERCC5 (0.49) | ERCC5FEN1HPGDGPR52MYC | |
| SCHEMBL7146890 | 0.76 | AKR1C1 (0.53) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8201571 | 0.76 | FOLH1 (0.33) | ERCC5FEN1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL8201573 | 0.76 | FOLH1 (0.33) | ERCC5FEN1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9493449 | 0.74 | KMT2A (0.46) | ERCC5FEN1HPGDGPR52MYC | |
| SCHEMBL7770355 | 0.74 | ERCC5 (0.46) | ERCC5FEN1HPGDGPR52MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021399-A2 | FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS | AVENTIS CROPSCIENCE S.A. (FR) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015512-A2 | FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS | RHONE POULENC AGROCHIMIE (FR) | 1998-04-16 | — | — | WO | disclosed |