Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201571 | 1.00 | FOLH1 (0.33) | FOLH1PTPN1ERCC5FEN1CES1 | |
| SCHEMBL3459412 | 0.80 | FOLH1 (0.37) | FOLH1PTPN1ERCC5FEN1CES1 | |
| SCHEMBL7459530 | 0.80 | FOLH1 (0.37) | FOLH1PTPN1ERCC5FEN1CES1 | |
| SCHEMBL7691194 | 0.76 | ERCC5 (0.36) | FOLH1PTPN1ERCC5FEN1AKR1C1 | |
| SCHEMBL8208906 | 0.76 | ERCC5 (0.45) | ERCC5FEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8208899 | 0.76 | ERCC5 (0.45) | ERCC5FEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL5080478 | 0.75 | ALDH1A1 (0.39) | FOLH1ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL3459410 | 0.75 | ALDH1A1 (0.39) | FOLH1ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL7459526 | 0.75 | ALDH1A1 (0.39) | FOLH1ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL9490817 | 0.73 | ALDH1A1 (0.37) | FOLH1ALDH1A1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021399-A2 | FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS | AVENTIS CROPSCIENCE S.A. (FR) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015512-A2 | FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS | RHONE POULENC AGROCHIMIE (FR) | 1998-04-16 | — | — | WO | disclosed |