Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | HRH2 | P25021 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865505 | 1.00 | LMNA (0.54) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL306889 | 0.79 | LMNA (0.55) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL2051128 | 0.79 | LMNA (0.55) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL306888 | 0.79 | LMNA (0.55) | LMNAPOLBGAAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL1032722 | 0.78 | LMNA (0.54) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL5207812 | 0.78 | PDK1 (0.62) | LMNAPOLBGAAMAPTTSHR | |
| Bromide SCHEMBL1193429 | 0.78 | LMNA (0.54) | LMNAPOLBGAAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL942873 | 0.78 | LMNA (0.54) | LMNAPOLBGAAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL27632975 | 0.78 | LMNA (0.54) | LMNAPOLBGAAMAPTTSHR | |
| Bromide SCHEMBL16061698 | 0.76 | LMNA (0.53) | LMNAPOLBGAAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008041240-A1 | PROCESS FOR PREPARING (S)-PRAMIPEXOLE AND ITS INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2008-04-10 | — | — | WO | disclosed |