SCHEMBL820949

SCHEMBL820949

COc1ccc(Oc2ccc(C(O)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.58
ALDH1A1 P00352 6/20 0.53
MAPT P10636 2/20 0.53
LTA4H P09960 2/20 0.50
RELA Q04206 1/20 0.47
SRD5A2 P31213 1/20 0.46
TEAD4 Q15561 1/20 0.45
CYP19A1 P11511 1/20 0.45
BRD4 O60885 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
POLB P06746 1/20 0.44
AOC3 Q16853 2/20 0.43
PARP10 Q53GL7 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19191531 0.95 ACHE (0.52) ACHEALDH1A1MAPTLTA4HRELA
SCHEMBL28973547 0.94 ACHE (0.65) ACHEALDH1A1MAPTRELACYP19A1
SCHEMBL8805726 0.94 ACHE (0.65) ACHEALDH1A1MAPTRELACYP19A1
SCHEMBL29975972 0.92 LTA4H (0.58) ALDH1A1LTA4HSRD5A2TDP1AOC3
SCHEMBL25574740 0.92 LTA4H (0.58) ALDH1A1LTA4HSRD5A2TDP1AOC3
SCHEMBL120187 0.85 CA12 (0.58) ACHEALDH1A1TDP1AOC3CA12
SCHEMBL25873960 0.85 LTA4H (0.73) ALDH1A1LTA4HSRD5A2BRD4GAA
SCHEMBL18383076 0.85 LTA4H (0.50) ALDH1A1LTA4HSRD5A2TDP1AOC3
SCHEMBL12277315 0.83 ACHE (0.83) ACHEALDH1A1MAPTLTA4HRELA
SCHEMBL257625 0.83 ACHE (0.83) ACHEALDH1A1MAPTLTA4HRELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2758448-B1 SULFONIC ACID GROUP-CONTAINING POLYMER, SULFONIC ACID GROUP-CONTAINING AROMATIC COMPOUND AND METHOD OF MAKING THE SAME, AS WELL AS POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE MOLDED PRODUCT AND SOLID POLYMER FUEL CELL USING THE SAME TORAY INDUSTRIES (JP) 2017-08-02 EP disclosed
US-8795841-B2 Graft polymerization method and product obtained thereby JAPAN MEDICAL MATERIALS CORPORATION (JP) 2014-08-05 US disclosed
US-8765265-B2 Polymer sliding material, artificial joint member, medical appliance, and manufacturing method therefor KYOCERA MEDICAL CORPORATION (JP) 2014-07-01 US disclosed
US-20120197407-A1 HIGHLY LUBRICATING SLIDING MEMBER AND ARTIFICAL JOINT USING SAME THE UNIVERSITY OF TOKYO (JP) 2012-08-02 US disclosed
US-20120022665-A1 POLYMER SLIDING MATERIAL, ARTIFICIAL JOINT MEMBER, MEDICAL APPLIANCE, AND MANUFACTURING METHOD THEREFOR KYOCERA CORPORATION (JP) 2012-01-26 US disclosed
US-20110274940-A1 GRAFT POLYMERIZATION METHOD AND PRODUCT OBTAINED THEREBY KYOCERA CORPORATION (JP) 2011-11-10 US disclosed