Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | TP53 | P04637 | 2/20 | 0.75 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.58 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.58 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329340 | 0.86 | RAB9A (1.00) | RAB9ASMN1; SMN2TP53BCHETRPC3 | |
| SCHEMBL3593419 | 0.86 | RAB9A (1.00) | RAB9ASMN1; SMN2TP53BCHETRPC3 | |
| SCHEMBL31147200 | 0.83 | RAB9A (0.71) | RAB9ASMN1; SMN2TP53BCHETRPC3 | |
| SCHEMBL2674051 | 0.83 | RAB9A (0.71) | RAB9ASMN1; SMN2TP53BCHETRPC3 | |
| SCHEMBL27898217 | 0.81 | BCHE (0.68) | RAB9ASMN1; SMN2TP53BCHETRPC3 | |
| SCHEMBL178883 | 0.78 | BCHE (0.56) | RAB9ASMN1; SMN2TP53BCHETRPC3 | |
| SCHEMBL10069522 | 0.78 | SLC2A1 (0.66) | RAB9ASMN1; SMN2TP53BCHETRPC3 | |
| SCHEMBL15416993 | 0.78 | RAB9A (0.82) | RAB9ASMN1; SMN2TP53BCHETRPC3 | |
| SCHEMBL20707630 | 0.78 | RAB9A (0.67) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL6034415 | 0.77 | BCHE (0.72) | RAB9ASMN1; SMN2TP53BCHETRPC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000071522-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS METHIONYL T-RNA SYNTHETASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-30 | — | — | WO | disclosed |