Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487468 | 0.85 | IDO1 (0.48) | ERN1FFAR1IDO1AGXTMAOB | |
| SCHEMBL6600052 | 0.83 | ERN1 (0.43) | ERN1FFAR1IDO1AGXTMAOA | |
| SCHEMBL12345478 | 0.82 | MAOB (0.39) | MAOAMAOBLMNA | |
| SCHEMBL23478010 | 0.82 | ALDH1A1 (0.50) | ERN1ALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL28831709 | 0.81 | IDO1 (0.44) | ERN1FFAR1IDO1AGXTF2 | |
| SCHEMBL12345479 | 0.81 | CHRM2 (0.40) | ALDH1A1 | |
| SCHEMBL14230490 | 0.79 | ERN1 (0.42) | ERN1IDO1AGXTMAOAMAOB | |
| SCHEMBL30800165 | 0.78 | MAOA (0.55) | ERN1MAOAMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL1279762 | 0.78 | MAOA (0.55) | ERN1MAOAMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL7930766 | 0.77 | MGLL (0.44) | IDO1ALDH1A1SMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093812-A | LACTAMIZATION OF A 2-HYDROXYALKYLAMIDE IN AQUEOUS SOLUTION BY TREATMENT WITH A POLYCHLOROBENZOYL CHLORIDE, BASE AND PHASE TRANSFER AGENT | SCHERING CORPORATION (US) | 2000-07-25 | — | — | US | disclosed |
| US-5561227-A | CHLORINATION A CARBOXYLIC ACID; DEPROTONATION A CHIRAL (OXA OR THIA)ZOLIDINONE; ENOLIZING; CYCLIZATION | SCHERING CORPORATION (US) | 1996-10-01 | — | — | US | disclosed |
| US-5306817-A | Multistep; cyclizing a hydroxyamide by treating with a dialkylchlorophosphate either a metal hydride, or an aqueous solution of base and a phase transfer catalyst | SCHERING CORPORATION (US) | 1994-04-26 | — | — | US | disclosed |