Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191095 | 0.82 | TDP1 (0.45) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL8218173 | 0.82 | TDP1 (0.45) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL8198257 | 0.79 | TDP1 (0.43) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL8206768 | 0.77 | ALDH1A1 (0.60) | TDP1RAB9AALDH1A1HSD17B10HPGD | |
| SCHEMBL29556865 | 0.67 | CA12 (0.64) | TDP1SMN1; SMN2CA12CA9AKR1B1 | |
| SCHEMBL14876148 | 0.67 | TDP1 (0.64) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL30097232 | 0.66 | CA12 (0.66) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL4303689 | 0.66 | CA12 (0.66) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL31050182 | 0.64 | KMT2A (0.64) | CA12CA9RAB9AALDH1A1KMT2A | |
| SCHEMBL4234439 | 0.63 | ATM (0.68) | TDP1SMN1; SMN2CA12CA9ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799246-B1 | IMPROVED MUTABLE COMPOSITION | KIMBERLY CLARK CO (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-1020478-A1 | Method of making a substrate comprising a colored composition by using an improved mutable composition and so produced substrate | Kimberly-Clark Worldwide, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |