Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191095 | 0.86 | TDP1 (0.45) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL8210374 | 0.82 | TDP1 (0.47) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL8198257 | 0.82 | TDP1 (0.43) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL8218171 | 0.78 | ALDH1A1 (0.57) | TDP1RAB9ALMNAPKMALDH1A1 | |
| SCHEMBL29556865 | 0.66 | CA12 (0.64) | TDP1SMN1; SMN2CA12CA9AKR1B1 | |
| SCHEMBL14876148 | 0.66 | TDP1 (0.64) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL4303689 | 0.65 | CA12 (0.66) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL30097232 | 0.65 | CA12 (0.66) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL358896 | 0.63 | CYP3A4 (0.53) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7696703 | 0.62 | ALDH1A1 (0.57) | TDP1NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830638-B1 | PRE-DYES AND COMPOSITIONS COMPRISING THEM | KIMBERLY CLARK CO (US) | 2000-08-23 | — | — | EP | claimed |