Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198257 | 0.89 | TDP1 (0.43) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL8218173 | 0.86 | TDP1 (0.45) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL8210374 | 0.82 | TDP1 (0.47) | TDP1SMN1; SMN2CA12CA9NPC1 | |
| SCHEMBL7696703 | 0.78 | ALDH1A1 (0.57) | TDP1NPC1RAB9AKMT2AHPGD | |
| SCHEMBL21679595 | 0.75 | PPARG (0.41) | NPC1RAB9ALMNAPKMMAPT | |
| SCHEMBL8205701 | 0.75 | HPGD (0.64) | TDP1SMN1; SMN2NPC1RAB9AATM | |
| SCHEMBL19998344 | 0.70 | PKM (0.64) | NPC1RAB9AKMT2ALMNAPKM | |
| SCHEMBL20006396 | 0.68 | MAPT (0.47) | RAB9ALMNAPKMALDH1A1MAPT | |
| SCHEMBL12994172 | 0.67 | PKM (0.53) | SMN1; SMN2NPC1RAB9AKMT2ALMNA | |
| SCHEMBL7778728 | 0.67 | ALDH1A1 (0.54) | TDP1NPC1RAB9AKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767803-B1 | METHOD OF GENERATING A REACTIVE SPECIES AND APPLICATIONS THEREFOR | KIMBERLY CLARK CO (US) | 2000-08-23 | — | — | EP | claimed |
| EP-0994125-A1 | Method of generating a reactive species and applications thereof | KIMBERLY-CLARK CORPORATION (US) | 2000-04-19 | — | — | EP | claimed |
| EP-0799246-B1 | IMPROVED MUTABLE COMPOSITION | KIMBERLY CLARK CO (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-1020478-A1 | Method of making a substrate comprising a colored composition by using an improved mutable composition and so produced substrate | Kimberly-Clark Worldwide, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |