Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210584 | 0.86 | MAPT (0.37) | RAB9AKMT2AMEN1LMNAMAPT | |
| SCHEMBL6187402 | 0.84 | MAPT (0.40) | ALDH1A1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL8206799 | 0.81 | KDM4E (0.42) | ALDH1A1LMNAMAPTTSHRMAPK1 | |
| SCHEMBL6189547 | 0.81 | MRGPRX4 (0.41) | LMNAMAPTGAACYP1A2CYP2C9 | |
| SCHEMBL6191680 | 0.81 | GAA (0.41) | LMNAMAPTL3MBTL1GAACYP1A2 | |
| SCHEMBL27513415 | 0.80 | RAB9A (0.37) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL6188662 | 0.80 | GAA (0.40) | ALDH1A1RAB9AGAA | |
| SCHEMBL6188620 | 0.79 | HPGD (0.40) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL6192565 | 0.77 | BCL2 (0.46) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6186419 | 0.76 | HDAC1 (0.43) | ALDH1A1LMNAMAPTGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |