Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185337 | 0.94 | KDM4E (0.45) | KDM4ECNR1CTSLIDO1ALDH1A1 | |
| SCHEMBL8205220 | 0.89 | CA1 (0.42) | KDM4ECNR1CNR2IDO1SIGMAR1 | |
| SCHEMBL6188694 | 0.88 | CTSL (0.41) | KDM4ECTSLIDO1ALDH1A1LMNA | |
| SCHEMBL6188262 | 0.83 | CA2 (0.44) | KDM4EIDO1ALDH1A1LMNAPKM | |
| SCHEMBL28745235 | 0.83 | GAA (0.40) | KDM4ECTSLIDO1ALDH1A1LMNA | |
| SCHEMBL7665564 | 0.82 | AAK1 (0.39) | KDM4ECTSLIDO1ALDH1A1HPGD | |
| SCHEMBL8210587 | 0.81 | ALDH1A1 (0.39) | KDM4EALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL6188601 | 0.81 | GLS (0.42) | KDM4ECTSLALDH1A1LMNABRD4 | |
| SCHEMBL11952529 | 0.80 | KDM4E (0.58) | KDM4ECTSLSIGMAR1ALDH1A1LMNA | |
| SCHEMBL8211448 | 0.80 | DHFR (0.36) | SIGMAR1MAPTCA1CA2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |