Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727664 | 0.92 | GAA (0.50) | GAANPSR1TDP1ALDH1A1MAPT | |
| SCHEMBL8210672 | 0.84 | GAA (0.58) | GAANPSR1TDP1ALDH1A1MAPT | |
| SCHEMBL25342487 | 0.82 | GAA (0.51) | GAANPSR1TDP1ALDH1A1MAPT | |
| SCHEMBL12026292 | 0.80 | PLK1 (0.43) | GAANPSR1TDP1ALDH1A1MAPT | |
| SCHEMBL12026317 | 0.79 | RRM1 (0.54) | GAANPSR1TDP1ALDH1A1MAPT | |
| SCHEMBL17166582 | 0.79 | GAA (0.48) | GAANPSR1TDP1ALDH1A1MAPT | |
| SCHEMBL12026319 | 0.79 | GAA (0.49) | GAANPSR1TDP1ALDH1A1MAPT | |
| SCHEMBL12026303 | 0.76 | GAA (0.46) | GAANPSR1TDP1ALDH1A1MAPT | |
| SCHEMBL8223150 | 0.76 | GAA (0.60) | GAANPSR1TDP1ALDH1A1MAPT | |
| SCHEMBL12026302 | 0.76 | MAPT (0.54) | GAANPSR1TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110305632-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICAL BIS(THIOSEMICARBAZONES) | THE UNIVERSITY OF MELBOURNE (AU) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110305632-A1 | PROCESS FOR THE PREPARATION OF ASYMMETRICAL BIS(THIOSEMICARBAZONES) | TST, TBCB, TPMT | GAA 2112/4885NPSR1 1933/4885TDP1 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.