Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680514 | 0.93 | NPSR1 (0.57) | NPSR1GAAPOLBTSHRALDH1A1 | |
| SCHEMBL10860507 | 0.89 | ALDH1A1 (0.49) | NPSR1GAAPOLBTSHRALDH1A1 | |
| SCHEMBL26813621 | 0.85 | CYP1A2 (0.48) | GAAPOLBTSHRALDH1A1ENPP1 | |
| SCHEMBL6374518 | 0.84 | GAA (0.59) | NPSR1GAAPOLBTSHRALDH1A1 | |
| SCHEMBL6814867 | 0.82 | ALDH1A1 (0.49) | NPSR1GAAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10939470 | 0.82 | ALDH1A1 (0.47) | NPSR1GAAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6906905 | 0.80 | CA1 (0.50) | GAAALDH1A1ENPP1 | |
| SCHEMBL18289524 | 0.80 | CA1 (0.50) | GAAALDH1A1ENPP1 | |
| SCHEMBL11372605 | 0.80 | ALDH1A1 (0.67) | NPSR1GAAPOLBTSHRALDH1A1 | |
| SCHEMBL3684459 | 0.79 | PPARA (0.51) | TSHRENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |