Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812749 | 0.88 | EDNRB (0.47) | ALDH1A1KMT2ALMNAMAPTPOLB | |
| SCHEMBL6994087 | 0.84 | LMNA (0.53) | ALDH1A1KMT2ALMNAMAPTPOLB | |
| SCHEMBL3681748 | 0.83 | TSHR (0.44) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL8210871 | 0.82 | NPSR1 (0.60) | ALDH1A1POLBSMN1; SMN2GAANPSR1 | |
| SCHEMBL2352786 | 0.81 | PTGS1 (0.49) | ALDH1A1KMT2ALMNAMAPTPOLB | |
| SCHEMBL457964 | 0.78 | LMNA (0.44) | ALDH1A1KMT2ALMNAMAPTPOLB | |
| SCHEMBL6809807 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL26813621 | 0.77 | CYP1A2 (0.48) | ALDH1A1KMT2ALMNAMAPTPOLB | |
| SCHEMBL7320143 | 0.77 | LMNA (0.51) | ALDH1A1KMT2ALMNAMAPTPOLB | |
| SCHEMBL2881816 | 0.77 | LMNA (0.43) | ALDH1A1KMT2ALMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |