SCHEMBL8210907

SCHEMBL8210907

O=C(Oc1cccc(Br)c1)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.68
CYP1A2 P05177 3/20 0.68
ALDH1A1 P00352 2/20 0.68
TSHR P16473 2/20 0.68
CYP2C19 P33261 2/20 0.68
CYP2C9 P11712 1/20 0.68
MAPT P10636 2/20 0.59
MEN1 O00255 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
GAA P10253 2/20 0.56
RECQL P46063 1/20 0.56
MRGPRX4 Q96LA9 1/20 0.51
HPGD P15428 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PARP10 Q53GL7 1/20 0.50
NSD2 O96028 1/20 0.50
CYP3A4 P08684 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4816596 0.89 KMT2A (0.59) KMT2ACYP1A2ALDH1A1TSHRCYP2C19
SCHEMBL1785471 0.87 KMT2A (0.69) KMT2AALDH1A1MAPTMEN1TDP1
SCHEMBL23064097 0.81 KMT2A (0.62) KMT2AALDH1A1MAPTMEN1TDP1
SCHEMBL8897103 0.81 AKR1C3 (0.67) KMT2AALDH1A1MAPTMEN1TDP1
SCHEMBL31888 0.80 PARP10 (0.70) KMT2AALDH1A1TSHRMAPTMEN1
SCHEMBL1870544 0.80 PARP10 (0.70) KMT2AALDH1A1TSHRMAPTMEN1
SCHEMBL8198250 0.80 KMT2A (0.61) KMT2AALDH1A1MAPTMEN1TDP1
Benzoic Acid 3-Hydroxyphenyl Ester SCHEMBL78117 0.80 ESR1 (0.71) KMT2AALDH1A1MAPTMEN1TDP1
SCHEMBL9356640 0.80 AKR1C3 (0.65) KMT2AALDH1A1MAPTMEN1TDP1
SCHEMBL7175937 0.80 ALOX5 (0.66) KMT2ACYP1A2ALDH1A1CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed