Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31722947 | 0.87 | USP2 (0.46) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL16862274 | 0.81 | KDM4E (0.41) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| Busulfan SCHEMBL28144825 | 0.72 | TSHR (0.75) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL18151741 | 0.71 | KDM4E (0.35) | KDM4E | |
| Hydrochloric Acid SCHEMBL28895013 | 0.69 | KDM4E (0.34) | KDM4E | |
| SCHEMBL25520674 | 0.69 | USP2 (0.48) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL20323423 | 0.68 | KDM4E (0.33) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL15605706 | 0.67 | USP2 (0.46) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL373746 | 0.67 | USP2 (0.46) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL1965412 | 0.67 | KDM4E (0.32) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482236-B | Indenone derivative and pharmaceutical composition comprising same | KOREA RES INST CHEM TECH | 2015-01-28 | — | — | CN | disclosed |
| US-8877747-B2 | Indenone derivative and pharmaceutical composition comprising same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2014-11-04 | — | — | US | disclosed |
| EP-2475649-B1 | INDENONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA RES INST CHEM TECH (KR) | 2014-08-13 | — | — | EP | disclosed |
| US-20120214991-A1 | Indenone Derivative and Pharmaceutical Composition Comprising Same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-08-23 | — | — | US | disclosed |
| EP-2475649-A1 | INDENONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Korea Research Institute Of Chemical Technology (KR) | 2012-07-18 | — | — | EP | disclosed |
| CN-102482236-A | Indanone derivatives and pharmaceutical compositions containing the same | KOREA RES INST CHEM TECH | 2012-05-30 | — | — | CN | disclosed |
| WO-2011030955-A1 | INDENONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214991-A1 | Indenone Derivative and Pharmaceutical Composition Comprising Same | INSR, HSD17B7, SOST | KDM4E 1070/4885USP2 4545/4885ALDH1A1 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.