Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212577 | 0.88 | HCAR3 (0.51) | HCAR3GAAKDM4EALDH1A1MAPT | |
| SCHEMBL1884486 | 0.79 | HCAR3 (0.48) | HCAR3GAAKDM4EALDH1A1TSHR | |
| SCHEMBL16801640 | 0.77 | HCAR3 (0.57) | HCAR3GAAKDM4EALDH1A1MAPT | |
| SCHEMBL14879908 | 0.75 | TTR (0.53) | MAPTTSHRTP53LMNA | |
| SCHEMBL2741948 | 0.75 | LMNA (0.47) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL472266 | 0.74 | EGFR (0.58) | GAAKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL900921 | 0.73 | RARB (0.50) | GAAKDM4EALDH1A1MAPTTHRB | |
| SCHEMBL15840793 | 0.73 | HCAR3 (0.50) | HCAR3GAAKDM4EALDH1A1TSHR | |
| SCHEMBL17737095 | 0.73 | KDM4E (0.50) | GAAKDM4EALDH1A1TSHRTP53 | |
| SCHEMBL8380045 | 0.73 | ALDH1A1 (0.45) | HCAR3GAAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6036729-A | DYEING, SOAKING MATERIAL WITH NAPHTHOLS, HYDROGEN PEROXIDE AND ENZYMES OF PEROXIDASE OR OXIDASE | NOVO NORDISK A/S (DK) | 2000-03-14 | — | — | US | disclosed |