Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | AQP1 | P29972 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 4/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211086 | 0.87 | AQP1 (0.35) | NFKB1NFKB2RELAAQP1TDP1 | |
| SCHEMBL8210625 | 0.87 | CES1 (0.42) | NFKB1NFKB2RELAAQP1TDP1 | |
| SCHEMBL5324231 | 0.83 | NFKB1 (0.46) | NFKB1NFKB2RELAAQP1TDP1 | |
| SCHEMBL8212877 | 0.80 | AQP1 (0.43) | NFKB1NFKB2RELAAQP1TDP1 | |
| SCHEMBL8202637 | 0.80 | AQP1 (0.43) | NFKB1NFKB2RELAAQP1TDP1 | |
| SCHEMBL8223394 | 0.75 | AQP1 (0.46) | NFKB1NFKB2RELAAQP1TDP1 | |
| SCHEMBL8228892 | 0.75 | DRD2 (0.43) | NFKB1NFKB2RELAAQP1TDP1 | |
| SCHEMBL4622511 | 0.74 | AQP1 (0.59) | NFKB1NFKB2RELAAQP1TDP1 | |
| SCHEMBL8213039 | 0.73 | AQP1 (0.42) | NFKB1NFKB2RELAAQP1TDP1 | |
| Hydrochloric Acid SCHEMBL4622531 | 0.73 | AQP1 (0.58) | NFKB1NFKB2RELAAQP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052087-A1 | CHROMANE DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |