Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568388 | 0.89 | GAA (0.55) | GAAMAPTMAOAMAOBCREBBP | |
| SCHEMBL5568385 | 0.89 | GAA (0.55) | GAAMAPTMAOAMAOBCREBBP | |
| SCHEMBL7039228 | 0.73 | L3MBTL1 (0.51) | MAOAMAOBCREBBP | |
| SCHEMBL31627898 | 0.72 | HDAC8 (0.57) | MAOAMAOBSCN3A | |
| SCHEMBL11071303 | 0.72 | MAPT (0.49) | GAAMAPT | |
| SCHEMBL28923896 | 0.71 | CREBBP (0.67) | MAOAMAOBCREBBPKDM1A | |
| SCHEMBL31444075 | 0.71 | CREBBP (0.67) | MAOAMAOBCREBBPKDM1A | |
| SCHEMBL12420717 | 0.71 | MAPT (0.49) | GAAMAPTCREBBP | |
| Trifluoroacetic Acid SCHEMBL30188640 | 0.70 | MAOA (0.50) | MAOAMAOB | |
| SCHEMBL7037302 | 0.70 | GAA (0.55) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042288-A1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033801-A1 | TRIPEPTIDYL PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1999-07-08 | — | — | WO | disclosed |