Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3338067 | 0.77 | — | — | |
| SCHEMBL7541420 | 0.76 | TSHR (0.40) | MCL1TSHR | |
| SCHEMBL28624365 | 0.72 | LMNA (0.42) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28617313 | 0.72 | LMNA (0.42) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28273884 | 0.72 | LMNA (0.42) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28624366 | 0.72 | LMNA (0.42) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5269325 | 0.72 | LMNA (0.42) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2503275 | 0.72 | LMNA (0.42) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29206695 | 0.72 | LMNA (0.42) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11380649 | 0.72 | MCL1 (0.39) | MCL1LMNACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025202985-A1 | PROCESS FOR THE PREPARATION AND PURIFICATION OF CRYSTALLINE RESMETIROM | MOREPEN LABORATORIES LIMITED (IN) | 2025-10-02 | — | — | WO | disclosed |
| US-12358899-B2 | Thyroid hormone receptor agonists and uses thereof | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2025-07-15 | — | — | US | disclosed |
| EP-4574208-A2 | THYROID HORMONE RECEPTOR AGONISTS AND USES THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2025-06-25 | — | — | EP | disclosed |
| EP-4574821-A1 | THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF | Terns, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| EP-4529954-A2 | THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF | Terns, Inc. (US) | 2025-04-02 | — | — | EP | disclosed |
| EP-3807267-B1 | THYROID HORMONE RECEPTOR AGONISTS AND USES THEREOF | XIZANG HAISCO PHARMACEUTICAL CO LTD (CN) | 2025-03-19 | — | — | EP | disclosed |
| CN-119462615-A | Compound with parallel-cyclic pyridazinone structure, and preparation method and application thereof | 西安新通药物研究股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119431265-A | Compound as thyroid hormone receptor agonist | 南京瑞捷医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-113474335-B | Compounds and their use as thyroid hormone receptor agonists | 南京瑞捷医药科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| US-20240360106-A1 | THYROID HORMONE RECEPTOR AGONISTS AND USES THEREOF | XIZANG HAISCO PHARMACEUTICAL CO LTD (CN) | 2024-10-31 | — | — | US | disclosed |
| US-5214043-A | Controlling parasitic protozoa and fish parasites | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| US-5114938-A | Antiprotozoa agents and parasiticides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-05-19 | — | — | US | disclosed |
| US-5070091-A | HONEY BEES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| US-4968795-A | PARASITICIDES, ANTIPROTOZOA AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| US-4935423-A | Antiprotozoa agent | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-19 | — | — | US | disclosed |
| EP-0008277-B1 | BENZOPYRANO DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR PREPARING THE COMPOUNDS AND COMPOSITIONS | Technobiotic Ltd. (CH) | 1981-09-02 | — | — | EP | disclosed |
| US-4272535-A | 2,4-[1H,3H,5H]-(1)-Benzopyrano-[2,3-d]-pyrimidinediones and their use as anti-allergy agents | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| EP-0008277-A1 | Benzopyrano derivatives, pharmaceutical compositions containing them and processes for preparing the compounds and compositions | Technobiotic Ltd. (CH) | 1980-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360106-A1 | THYROID HORMONE RECEPTOR AGONISTS AND USES THEREOF | TSHR, THRA, TRHR | MCL1 4860/4885LMNA 3364/4885CHRM2 589/4885 |
| US-12358899-B2 | Thyroid hormone receptor agonists and uses thereof | TSHR, THRA, TRHR | MCL1 4860/4885LMNA 3364/4885CHRM2 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.