Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25724320 | 0.80 | NOS2 (0.39) | HTR2AHTR2CNOS3NOS2MTNR1A | |
| SCHEMBL8205349 | 0.76 | HTR2A (0.37) | HTR2AHTR2CDYRK1A | |
| SCHEMBL19700546 | 0.75 | NOS3 (0.38) | HTR2AHTR2CNOS3NOS2 | |
| SCHEMBL20836980 | 0.71 | HTR2A (0.35) | HTR2AHTR2CDYRK1A | |
| SCHEMBL20296468 | 0.71 | MAPT (0.36) | NOS3NOS2 | |
| SCHEMBL8216040 | 0.71 | GABRA1 (0.33) | HTR2AHTR2C | |
| SCHEMBL10054248 | 0.71 | HTR2A (0.39) | HTR2AHTR2CDYRK1AMTNR1AMTNR1B | |
| SCHEMBL24489810 | 0.70 | HTR2A (0.36) | HTR2AHTR2CMTNR1AMTNR1B | |
| SCHEMBL30117633 | 0.68 | NOS3 (0.41) | NOS3NOS2 | |
| SCHEMBL215981 | 0.68 | NOS3 (0.41) | NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110952-A | PREVENTING OR TREATING NASAL CONGESTION, OTITIS MEDIA AND SINUSITIS WITHOUT UNDESIRED SIDE EFFECTS, ALSO ASTHMA, PAIN, MIGRAINE, SUBSTANCE ABUSE AND ADDICTION, GASTROINTESTINAL DISORDER, ULCER, STOMACH HYPERACIDITY | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-29 | — | — | US | disclosed |
| CN-1242015-A | 2-imidazolinylaminobenzoxazole compounds useful as alpha-2 adrenoceptor agonists | PROCTER & GAMBLE (US) | 2000-01-19 | — | — | CN | disclosed |
| EP-0944622-A1 | 2-IMIDAZOLINYLAMINOBENZOXAZOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023611-A1 | 2-IMIDAZOLINYLAMINOBENZOXAZOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |