Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029110 | 0.98 | ALOX5 (0.46) | ALOX5TYRCYP3A4MEN1TP53 | |
| SCHEMBL9786790 | 0.98 | ALOX5 (0.46) | ALOX5TYRCYP3A4MEN1TP53 | |
| SCHEMBL18889039 | 0.87 | ALOX5 (0.50) | ALOX5TYRCYP3A4MEN1TP53 | |
| SCHEMBL19000284 | 0.80 | ALOX5 (0.39) | ALOX5TYRCYP3A4MEN1TP53 | |
| SCHEMBL15437715 | 0.80 | ALOX5 (0.50) | ALOX5TYRCYP3A4MEN1TP53 | |
| SCHEMBL11682168 | 0.79 | TYR (0.50) | ALOX5TYRCYP3A4MEN1TP53 | |
| SCHEMBL19000281 | 0.79 | ALOX5 (0.38) | ALOX5TYRCYP3A4MEN1TP53 | |
| SCHEMBL7138144 | 0.78 | RXRA (0.42) | ALOX5TYRCYP3A4MEN1TP53 | |
| SCHEMBL28468210 | 0.78 | ALOX5 (0.44) | ALOX5TYRCYP3A4MEN1TP53 | |
| SCHEMBL4459351 | 0.77 | LIPG (0.55) | ALOX5PTGS2LIPGTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153322-A | Methods for making fluorinated surface modifying agents, methods of using same and products made using same | HOUSTON, UNIVERSITY OF | 2000-11-28 | — | — | US | disclosed |