Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | TERT | O14746 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.56 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.56 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.56 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CBFB | Q13951 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355532 | 0.88 | TERT (0.72) | NPC1RAB9ALMNASMN1; SMN2TERT | |
| SCHEMBL1783365 | 0.82 | SMN1; SMN2 (0.57) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL675018 | 0.81 | ENPP2 (0.71) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9858666 | 0.81 | ENPP2 (0.71) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9510547 | 0.81 | ENPP2 (0.71) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1781479 | 0.80 | SMN1; SMN2 (0.55) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL24527544 | 0.80 | TERT (0.60) | NPC1RAB9ALMNATERTKDM4E | |
| SCHEMBL7203505 | 0.79 | RAB9A (1.00) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL1782973 | 0.79 | SMN1; SMN2 (0.54) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL10313322 | 0.79 | TERT (0.67) | NPC1RAB9ATERTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143570-A | TRANSPARENT SUPPORT COATED WITH TRANSPARENT COATING OF PLASTICIZER-FREE HYDROPHOBIC POLYMER HAVING SPECIFIC GLASS TRANSITION TEMPERATURE, COUNTERIONS IN THE FORM OF LIPOPHILIC SALTS, IONOPHORE, AND SPECIFIC FLUOROPHORES | NOVARTIS CORPORATION (US) | 2000-11-07 | — | — | US | disclosed |
| EP-0758450-B1 | OPTICAL SENSOR FOR THE DETERMINATION OF IONS | CIBA GEIGY AG (CH) | 1998-08-05 | — | — | EP | disclosed |
| EP-0758450-A1 | OPTICAL SENSOR FOR THE DETERMINATION OF IONS | Novartis AG (CH) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995026501-A1 | OPTICAL SENSOR FOR THE DETERMINATION OF IONS | CIBA-GEIGY AG (CH) | 1995-10-05 | — | — | WO | disclosed |
| EP-0623599-A1 | Optical sensors for the determination of cations | CIBA-GEIGY AG (CH) | 1994-11-09 | — | — | EP | disclosed |