Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669311 | 0.84 | KMT2A (0.47) | CCR2KMT2ALMNATAS1R3TAS1R1 | |
| SCHEMBL9231470 | 0.81 | GAA (0.46) | GRIK1CCR2KMT2AGAALMNA | |
| SCHEMBL27614646 | 0.78 | CA3 (0.42) | KMT2ALMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1337289 | 0.76 | IDO1 (0.41) | GRIK1CCR2KMT2AGAALMNA | |
| SCHEMBL28664691 | 0.76 | CXCR2 (0.39) | GRIK1CCR2KMT2AGAANPC1 | |
| Hydrochloric Acid SCHEMBL3641623 | 0.74 | IDO1 (0.40) | GRIK1CCR2KMT2AGAALMNA | |
| SCHEMBL28172323 | 0.73 | TP53 (0.48) | KMT2AGAALMNANPC1HPGD | |
| SCHEMBL12883495 | 0.71 | CCR2 (0.42) | GRIK1CCR2KMT2AGAALMNA | |
| SCHEMBL12368470 | 0.71 | NR4A2 (0.40) | GRIK1CCR2KMT2AGAALMNA | |
| SCHEMBL12895731 | 0.71 | ALDH1A1 (0.40) | GRIK1CCR2KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470526-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011025927-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2011-03-03 | — | — | WO | disclosed |