SCHEMBL8214696

SCHEMBL8214696

C=CN1C(=O)C2CCCCC2C1=O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
HTT P42858 1/20 0.33
MAPT P10636 2/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6050404 0.81 ALDH1A1 (0.37) ALDH1A1HTTLMNASMN1; SMN2PDE4A
SCHEMBL11324826 0.74 MT-CO2 (0.31) MAPT
SCHEMBL9117288 0.73 ALDH1A1 (0.35) ALDH1A1HTTMAPTLMNAMAPK1
SCHEMBL9114645 0.73 ALDH1A1 (0.35) ALDH1A1HTTMAPTLMNAMAPK1
SCHEMBL4337299 0.72 ALDH1A1 (0.41) ALDH1A1HTTSMN1; SMN2GAAHPGD
SCHEMBL25033807 0.71 ALDH1A1 (0.46) ALDH1A1HTTMAPTLMNAMAPK1
SCHEMBL6222332 0.71 ALDH1A1 (0.43) ALDH1A1HTTSMN1; SMN2GAAHPGD
SCHEMBL7284066 0.69 ALDH1A1 (0.43) ALDH1A1HTTMAPTLMNAMAPK1
SCHEMBL14806793 0.68 ALDH1A1 (0.35) ALDH1A1HTTMAPK1SMN1; SMN2PDE4A
SCHEMBL18072219 0.67 POLB (0.41) ALDH1A1HTTMAPTSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3094695-B1 WATERBORNE COATING COMPOSITION WITH IMPROVED OPEN TIME ALLNEX NETHERLANDS BV (NL) 2018-10-24 EP disclosed
US-20160333199-A1 WATERBORNE COATING COMPOSITION WITH IMPROVED OPEN TIME NUPLEX RESINS B.V. (NL) 2016-11-17 US disclosed
US-6140387-A RADIATING POLYVINYLCAPROLACTAM, POLYVINYL ETHER HOMO- OR COPOLYMERS,AN UNSATURATED COMPOUND, WATER AND/OR SOLVENT WITH HIGH-ENERGY LIGHT; SOLAR-ENERGY SYSTEMS; GLAZE BETWEEN WINDOW GLASS SHEETS; HEAT CONTROL; SWITCHES CLOUDINESS/CLARITY BASF AKTIENGESELLSCHAFT (DE) 2000-10-31 US disclosed
EP-0873367-A1 GELS WITH THERMOTROPIC PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 1998-10-28 EP disclosed
WO-1997025357-A1 GELS WITH THERMOTROPIC PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 1997-07-17 WO disclosed
WO-1997025358-A1 GELS WITH THERMOTROPIC PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 1997-07-17 WO disclosed
US-5587404-A IRRADIATING MIXTURE OF UNCROSSLINKED POLYMER, MONOMER CAPABLE OF FREE RADICAL POLYMERIZATION AND SOLVENT BASF AKTIENGESELLSCHAFT (DE) 1996-12-24 US disclosed
EP-0678534-A1 Gels having thermotropic properties BASF Aktiengesellschaft (DE) 1995-10-25 EP disclosed
US-4148845-A OIL ADDITIVES SOCIETE NATIONALE ELF AQUITAINE (FR) 1979-04-10 US disclosed
US-4139417-A Lubricating oil compositions containing copolymers of olefins or of olefins and non-conjugated dienes with unsaturated derivatives of cyclic imides SOCIETE NATIONALE ELF AQUITAINE (FR) 1979-02-13 US disclosed
US-4063010-A LUBRICANT ADDITIVES SOCIETE NATIONALE ELF AQUITAINE (SNEA) (FR) 1977-12-13 US disclosed