SCHEMBL4337299

SCHEMBL4337299

[CH2]N1C(=O)C2CCCCC2C1=O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
HTT P42858 1/20 0.35
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
KMT2A Q03164 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP1A2 P05177 1/20 0.31
STAT3 P40763 1/20 0.31
PPOX P50336 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6222332 0.77 ALDH1A1 (0.43) ALDH1A1HTTGAAHPGDSMN1; SMN2
SCHEMBL44008 0.72 POLB (0.41) ALDH1A1HTTGAAHPGDSMN1; SMN2
SCHEMBL12332676 0.72 ALDH1A1 (0.41) ALDH1A1HTTGAAHPGDSMN1; SMN2
SCHEMBL13239527 0.72 ALDH1A1 (0.41) ALDH1A1HTTSMN1; SMN2NPC1RAB9A
SCHEMBL18072219 0.72 POLB (0.41) ALDH1A1HTTGAAHPGDSMN1; SMN2
SCHEMBL6731258 0.72 ALDH1A1 (0.41) ALDH1A1HTTGAAHPGDSMN1; SMN2
SCHEMBL10715568 0.72 ALDH1A1 (0.45) ALDH1A1HTTGAAHPGDSMN1; SMN2
SCHEMBL761658 0.72 ALDH1A1 (0.41) ALDH1A1HTTSMN1; SMN2NPC1RAB9A
SCHEMBL13206576 0.72 ALDH1A1 (0.41) ALDH1A1HTTSMN1; SMN2NPC1RAB9A
SCHEMBL486926 0.72 POLB (0.41) ALDH1A1HTTGAAHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210321608-A1 PYRETHROID FORMULATIONS SILICON VALLEY BANK (CA) 2021-10-21 US disclosed
EP-2747556-B1 PYRETHROID FORMULATIONS VIVE CROP PROT INC (CA) 2021-08-11 EP disclosed
US-10966422-B2 Pyrethroid formulations VIVE CROP PROTECTION INC. (CA) 2021-04-06 US disclosed
EP-2048953-B1 INSECTICIDAL COMPOSITION MCLAUGHLIN GORMLEY KING CO (US) 2020-11-18 EP disclosed
US-20200138018-A1 PYRETHROID FORMULATIONS SILICON VALLEY BANK (CA) 2020-05-07 US disclosed
US-10455830-B2 Pyrethroid formulations VIVE CROP PROTECTION INC. (CA) 2019-10-29 US disclosed
US-20170360032-A1 PYRETHROID FORMULATIONS SILICON VALLEY BANK (CA) 2017-12-21 US disclosed
US-9686979-B2 Pyrethroid formulations VIVE CROP PROTECTION INC. (CA) 2017-06-27 US disclosed
US-20140187424-A1 PYRETHROID FORMULATIONS VIVE CROP PROTECTION INC. (CA) 2014-07-03 US disclosed
EP-2747556-A2 PYRETHROID FORMULATIONS Vive Crop Protection Inc. (CA) 2014-07-02 EP disclosed
US-20040209960-A1 Methods of treating lower urinary tract disorders using sodium channell modulators DYNOGEN PHARMACEUTICALS, INC. 2004-10-21 US disclosed
WO-2004066990-A2 METHODS OF TREATING LOWER URINARY TRACT DISORDERS USING SODIUM CHANNEL MODULATORS DYNOGEN PHARMACEUTICALS, INC. (US) 2004-08-12 WO disclosed
WO-2004066987-A2 USE OF SODIUM CHANNEL MODULATORS FOR TREATING GASTROINTESTINAL TRACT DISORDERS DYNOGEN PHARMACEUTICALS, INC. (US) 2004-08-12 WO disclosed
US-5506269-A Parasiticide employing pyrethroid type compounds MITSUI TOATSU CHEMICALS, INC. (JP) 1996-04-09 US disclosed
EP-0665011-A1 Parasiticide against endoparasites comprising a pyrethroid type compound MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-08-02 EP disclosed
US-5128329-A Fenitrothion, sorbitan monooleate, xanthan gum SUMITOMO CORPORATION (JP) 1992-07-07 US disclosed
EP-0131762-A1 Agricultural chemical preparation in the form of aqueous suspension Sumitomo Corporation (JP) 1985-01-23 EP disclosed
US-4000266-A (1-CYCLOHEXENE-1,2-DICARBOXAMIDO)METHYL CHRYSANTHEMUMATE, (5-BENZYL-3-FURYL)METHYL CHRYSANTHEMUMATE FMC CORPORATION (US) 1976-12-28 US disclosed
US-4000266-A (1-CYCLOHEXENE-1,2-DICARBOXAMIDO)METHYL CHRYSANTHEMUMATE, (5-BENZYL-3-FURYL)METHYL CHRYSANTHEMUMATE FMC CORPORATION (US) 1976-12-28 US disclosed
US-3944666-A Insecticidal compositions and methods of combatting insects using 3-phenoxybenzyl 2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropanecarboxylate insecticide with a synergistic compound of mono (alkyl and alkenyl)mono omega-alkynyl arylphosphonates FMC CORPORATION (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140187424-A1 PYRETHROID FORMULATIONS DDT, PCNP, MGST3 ALDH1A1 2794/4885HTT 2171/4885GAA 2021/4885
US-20170360032-A1 PYRETHROID FORMULATIONS DDT, PCNP, MGST3 ALDH1A1 2794/4885HTT 2171/4885GAA 2021/4885
US-20210321608-A1 PYRETHROID FORMULATIONS DDT, PCNP, MGST3 ALDH1A1 2794/4885HTT 2171/4885GAA 2021/4885
US-10966422-B2 Pyrethroid formulations DDT, PCNP, MGST3 ALDH1A1 2794/4885HTT 2171/4885GAA 2021/4885
US-20200138018-A1 PYRETHROID FORMULATIONS DDT, PCNP, MGST3 ALDH1A1 2794/4885HTT 2171/4885GAA 2021/4885
US-20040209960-A1 Methods of treating lower urinary tract disorders using sodium channell modulators CACNA1G, CACNA1D, CACNA1B ALDH1A1 1586/4885HTT 1018/4885GAA 1563/4885
US-10455830-B2 Pyrethroid formulations DDT, PCNP, MGST3 ALDH1A1 2794/4885HTT 2171/4885GAA 2021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.