SCHEMBL8214932

SCHEMBL8214932

NS(=O)(=O)c1ccc(C2CNCCO2)cc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.47
DRD3 P35462 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27845784 0.84
SCHEMBL7007529 0.84 SLC6A3 (0.49)
SCHEMBL322881 0.82 DRD2 (0.48) DRD2DRD3
SCHEMBL12695816 0.78 DRD2 (0.53) DRD2DRD3
SCHEMBL3404764 0.78 DRD2 (0.53) DRD2DRD3
SCHEMBL82902 0.78 DRD2 (0.53) DRD2DRD3
SCHEMBL322716 0.77 DRD2 (0.47) DRD2DRD3
Hydrochloric Acid SCHEMBL13505422 0.77 DRD2 (0.51) DRD2DRD3
Hydrochloric Acid SCHEMBL83201 0.77 DRD2 (0.51) DRD2DRD3
SCHEMBL134338 0.76 DRD2 (0.54) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000023444-A1 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS ABBOTT LABORATORIES (US) 2000-04-27 WO claimed
WO-2000023444-A1 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS ABBOTT LABORATORIES (US) 2000-04-27 WO disclosed