Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232524 | 0.83 | TSHR (0.36) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL15401917 | 0.83 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL235402 | 0.82 | TSHR (0.36) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL13330235 | 0.80 | TSHR (0.35) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL284885 | 0.79 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL1799910 | 0.79 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL71730 | 0.79 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL28328024 | 0.79 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL28971508 | 0.77 | ACHE (0.34) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL441818 | 0.77 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166236-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0757033-B1 | Vinyl carbonate and vinyl carbamate monomers for a contact lens material | BAUSCH & LOMB (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5610252-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0757033-A2 | Vinyl carbonate and vinyl carbamate monomers for a contact lens material | BAUSCH & LOMB INCORPORATED (US) | 1997-02-05 | — | — | EP | disclosed |
| US-5070215-A | Gas permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0396364-A2 | Novel vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1990-11-07 | — | — | EP | disclosed |