Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304203 | 0.88 | TDP1 (0.54) | TDP1ALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL15249360 | 0.86 | TDP1 (0.45) | TDP1ALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL13296152 | 0.83 | TDP1 (0.42) | TDP1ALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL6131221 | 0.81 | TDP1 (0.48) | TDP1ALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL4311541 | 0.81 | TDP1 (0.46) | TDP1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL19821867 | 0.81 | TDP1 (0.41) | TDP1ALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL30597601 | 0.81 | TDP1 (0.46) | TDP1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9826996 | 0.80 | TDP1 (0.44) | TDP1ALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL19821836 | 0.79 | TDP1 (0.40) | TDP1ALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL23818606 | 0.79 | TDP1 (0.47) | TDP1ALDH1A1USP2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | UMPS, PUF60, SMCHD1 | TDP1 2133/4885ALDH1A1 333/4885USP2 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.