SCHEMBL8215645

SCHEMBL8215645

CC(C)C1=CCC(C(C)C)=C1[Si](NC1CCCCC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
EPHX2 P34913 1/20 0.33
EPHX1 P07099 2/20 0.33
LMNA P02545 2/20 0.33
ALDH1A1 P00352 4/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C19 P33261 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP2C9 P11712 1/20 0.32
SCN1A P35498 1/20 0.31
SCN2A Q99250 1/20 0.31
SCN3A Q9NY46 1/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 2/20 0.30
HPGD P15428 1/20 0.30
MEN1 O00255 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8208156 0.86 L3MBTL1 (0.35) GAAL3MBTL1EPHX2EPHX1LMNA
SCHEMBL8215457 0.79 NPC1 (0.34) TSHRRAB9A
SCHEMBL8214785 0.78 GAA (0.30) GAA
SCHEMBL8208013 0.75 LMNA (0.38) GAAL3MBTL1EPHX2LMNAALDH1A1
SCHEMBL8208147 0.71 GAA (0.36) GAAL3MBTL1EPHX2EPHX1LMNA
SCHEMBL8219333 0.70 EPHX2 (0.33) GAAL3MBTL1EPHX2LMNAALDH1A1
SCHEMBL8216425 0.69 EPHX2 (0.40) GAAL3MBTL1EPHX2EPHX1LMNA
SCHEMBL8215394 0.68 EPHX2 (0.35) GAAL3MBTL1EPHX2EPHX1LMNA
Hydrochloric Acid SCHEMBL10318487 0.66
SCHEMBL11381460 0.65 EPHX2 (0.42) GAAL3MBTL1EPHX2EPHX1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136995-A Process for producing aminosilane compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-24 US disclosed